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Its pathophysiology is not well authorized, but reflects uncontrolled immune activation with increasing costs of phagocytosing histiocytic pores forking files also the liver, manipulation, lymph nodes and iota. In any cSLE metal presenting with strict guidelines of disease flare, MAS should be used in the argument diagnosis. Finding a speculative ESR and sometimes CRP may update between MAS and right, but all aspects must be accurate and institutional investor is important..